The slimy sculpin is a nocturnal fish that usually spends most of its time on the stream bottom and seeks shelter under rocks and logs, especially during spawning season. When it swims, it sometimes appears to be "hopping" along the bottom because of its inefficient ability to swim. This is partly due to the absence of a swim bladder, which normally gives buoyancy to a fish. The fish has been studied in waters where there is current freshwater acidification. Sculpin were found to be less active and have lower rates of reproduction when found in these waters. For these reasons, slimy sculpin have been identified as a good indicator species for changes in acidification among lakes, ponds, and streams.